June 2021:
Highlights
- We report on a patient with a single dose of vaccine against SARS-CoV-2.
- He developed relevant serum titer levels but died 4 weeks later.
- By postmortem molecular mapping, we found viral RNA in nearly all organs examined.
- However, we did not observe any characteristic morphological features of COVID-19.
- Immunogenicity might be elicited, while sterile immunity was not established.
Abstract
A previously symptomless 86-year-old man received the first dose of the BNT162b2 mRNA COVID-19 vaccine. He died 4 weeks later from acute renal and respiratory failure. …
Postmortem molecular mapping by real-time polymerase chain reaction revealed relevant SARS-CoV-2 cycle threshold values in all organs examined (oropharynx, olfactory mucosa, trachea, lungs, heart, kidney and cerebrum) except for the liver and olfactory bulb.
Cerebrum is another word for the largest part of the brain.
Sources:
- June 1, 2021. Torsten Hansen, Ulf Titze, Nidhi Su Ann Kulamadayil-Heidenreich, Sabine Glombitza, Johannes Josef Tebbe, Christoph Röcken, Birte Schulz, Michael Weise, and Ludwig Wilkens. “First Case of Postmortem Study in a Patient Vaccinated against SARS-CoV-2.” International Journal of Infectious Diseases 107 (June): 172–75.
https://doi.org/10.1016/j.ijid.2021.04.053.
Research Journal. - December 10, 2020. “BNT162b2 Vaccine Candidate Against COVID-19: Vaccines and Related Biological Products Advisory Committee.” Pfizer-BioNTech.
https://www.fda.gov/media/144325/download.
Food & Drug Administration, PDF.