Scientists report that NAC combined with bromelain inactivates SARS-CoV-2

This article discusses the research that combined two over-the-counter substances, Bromelain and NAC. The resulting mix called BromAc can break the bonds that keep the spike protein of the SARS-CoV-2 virus together.

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The study The Combination of Bromelain and Acetylcysteine (BromAc) Synergistically Inactivates SARS-CoV-2 was done in Australia and France. One of the lead authors is associated with Mucpharm in Sydney, Australia, which makes BromAc.

— Dr. Jesse Santiano, January 17, 2023

Severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection is the cause of a worldwide pandemic, currently with limited therapeutic options. The spike glycoprotein and envelope protein of SARS-CoV-2, containing disulfide bridges for stabilization, represent an attractive target as they are essential for binding to the ACE2 receptor in host cells present in the nasal mucosa. Bromelain and Acetylcysteine (BromAc) has synergistic action against glycoproteins by breakage of glycosidic linkages and disulfide bonds. We sought to determine the effect of BromAc on the spike and envelope proteins and its potential to reduce infectivity in host cells. Recombinant spike and envelope SARS-CoV-2 proteins were disrupted by BromAc. Spike and envelope protein disulfide bonds were reduced by Acetylcysteine. In in vitro whole virus culture of both wild-type and spike mutants, SARS-CoV-2 demonstrated a concentration-dependent inactivation from BromAc treatment but not from single agents.

— Akhter et. al.

So, clearly this is VERY good news. If we can literally DISSOLVE the Spike Protein before it interacts with our ACE2 (and clearly many other) receptors, then the Spike, in essence, becomes as the nonillions of other viruses on the planet that cannot enter our cells.

— Walter M. Chesnut

Sources:

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  March 1, 2021. Javed Akhter, Grégory Quéromès, Krishna Pillai, Vahan Kepenekian, Samina Badar, Ahmed H. Mekkawy, Emilie Frobert, Sarah J. Valle, and David L. Morris. “The Combination of Bromelain and Acetylcysteine (BromAc) Synergistically Inactivates SARS-CoV-2.” Viruses 13 (3): 425.
  https://doi.org/10.3390/v13030425.
  Research Journal.
• 
  January 17, 2023. Jesse Santiano. “Bromelain and Acetylcysteine Combined Destroy SARS-CoV-2 Spike Protein.” Jesse Santiano M.D. | Don’t Get Sick!.
  https://drjessesantiano.com/bromelain-and-acetylcysteine-combined-destroy-sars-cov-2-spike-protein/.
  General Website Link.
• 
  January 20, 2023. Walter M. Chesnut. “Friday Hope: Bromelain, NAC and Spike Disintegration.” Substack newsletter. WMC Research.
  https://wmcresearch.substack.com/p/friday-hope-bromelain-nac-and-spike.
  Blog.
• 
  January 25, 2023. Sarah Westall with Sharry Edwards. NEW STUDY: Stop Damage & Remove Spike Proteins & DNA Programmable Robot Math Matrix w/ Dr. Edwards. Sarah Westall. Runtime: 1:04:31.
  https://www.bitchute.com/video/wf5nrLntjPji/.
  Video.
• 
  January 26, 2023. Frank Yap. “Quercetin, Bromelain and NAC for COVID (2023).” COVID Advisor.
  https://covid19.onedaymd.com/2021/11/quercetin-bromelain-and-nac-for-covid.html.
  General Website Link.
• 
  March 7, 2023. Jesse Santiano. “How to Dose Nattokinase, Bromelain and NAC.” Jesse Santiano M.D. | Don’t Get Sick!
  https://drjessesantiano.com/how-to-dose-nattokinase-bromelain-and-nac/.
  General Website Link.

Related:

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  April 16, 2015. C. Agostinis, S. Zorzet, R. De Leo, G. Zauli, F. De Seta, and R. Bulla. “The Combination of N-Acetyl Cysteine, Alpha-Lipoic Acid, and Bromelain Shows High Anti-Inflammatory Properties in Novel in Vivo and in Vitro Models of Endometriosis.” Mediators of Inflammation 2015 (April): 918089.
  https://doi.org/10.1155/2015/918089.
  Research Journal.
• 
  December 21, 2016. Vida Mokhtari, Parvaneh Afsharian, Maryam Shahhoseini, Seyed Mehdi Kalantar, and Ashraf Moini. “A Review on Various Uses of N-Acetyl Cysteine.” Cell Journal (Yakhteh) 19 (1): 11–17.
  https://doi.org/10.22074/cellj.2016.4872.
  Research Journal.
• 
  August 20, 2021. Trina Ekawati Tallei, Fatimawali, Afriza Yelnetty, Rinaldi Idroes, Diah Kusumawaty, Talha Bin Emran, Talha Zahid Yesiloglu, Wolfgang Sipp, Shafi Mahmud, Taha Alqahtani, Ali M. Alqahtani, Saeed Asiri, Mohammed Rahmatullah, Rownak Jahan, Md. Arif Khan, and Ismail Celik. “An Analysis Based on Molecular Docking and Molecular Dynamics Simulation Study of Bromelain as Anti-SARS-CoV-2 Variants.” Frontiers in Pharmacology 12 (August).
  https://doi.org/10.3389/fphar.2021.717757.
  Research Journal.