spike proteins – Pandemic Timeline https://pandemictimeline.com Chronological Sequence of Events Sun, 08 Oct 2023 01:32:24 +0000 en-US hourly 1 https://wordpress.org/?v=6.5.3 https://pandemictimeline.com/wp-content/uploads/2021/06/Covid-150x150.ico spike proteins – Pandemic Timeline https://pandemictimeline.com 32 32 Pfizer files patent US6372224: Canine coronavirus S gene and uses therefor https://pandemictimeline.com/2000/01/pfizer-files-patent-6372224-canine-coronavirus-s-gene-and-uses-therefor/ Fri, 28 Jan 2000 00:00:58 +0000 https://pandemictimeline.com/?p=1417 From the patent: The present invention provides the amino acid and nucleotide sequences of a CCV spike gene, and compositions containing one or more fragments of the spike gene and encoded polypeptide for prophylaxis, diagnostic purposes and treatment of CCV infections. — Patent US6372224B1 This is the patent for the spike protein virus, a vaccine…

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From the patent:

The present invention provides the amino acid and nucleotide sequences of a CCV spike gene, and compositions containing one or more fragments of the spike gene and encoded polypeptide for prophylaxis, diagnostic purposes and treatment of CCV infections.

Patent US6372224B1

This is the patent for the spike protein virus, a vaccine for the canine Coronavirus, which is actually one of the multiple forms of Coronavirus.

From the Reiner/Martin interview:

But as you know, up until 1999, the topic of Coronavirus vs V [VSV?] the patenting activity around Coronavirus was uniquely applied to veterinary sciences. The first vaccine ever patented for Coronavirus was actually sought by Pfizer. The application for the first vaccine for Coronavirus, which was specifically this s spike protein. So the exact same thing that allegedly we have rushed into invention. The first application was filed January 28 2000, 21 years ago. So the idea that we we mysteriously stumbled on the the way to intervene on vaccines is not only ludicrous, it is incredulous because Timothy Millor, Sharon Klepfer, Albert Paul Reed, and Elaine Jones on January 28 2000, filed what ultimately was issued as US Patent 6372224 which was the spike protein virus, a vaccine for the canine Coronavirus, which is actually one of the multiple forms of Coronavirus. But as I said, the early work up until 1999 was largely focused in the area of vaccines for animals, the two animals receiving the most attention were probably Ralph Barics work on rabbits and the rabbit cardiomyopathy that was associated with significant problems among rabbit breeders, and then canine Coronavirus in Pfizer’s work to identify how to develop s and spike protein vaccine target candidates giving rise to the obvious evidence that says that neither the Coronavirus concept of a vaccine, nor the principle of the Coronavirus itself as a pathogen of interest with respect to the spike proteins behaviour is anything novel at all. As a matter of fact, it’s 22 years old, based on patent filings. What’s more problematic, and what is actually the most egregious problem is that Anthony Fauci and NIAID found the malleability of Coronavirus to be a potential candidate for HIV vaccines. And so SARS is actually not a natural progression of a zoonetic modification of Coronavirus.

Dr. David Martin at 02:53

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UNC Chapel Hill files patent US7279327: Methods for producing recombinant coronavirus https://pandemictimeline.com/2002/04/unc-chapel-hill-files-patent-7279327-methods-for-producing-recombinant-coronavirus/ Fri, 19 Apr 2002 00:00:25 +0000 https://pandemictimeline.com/?p=1910 A helper cell for producing an infectious, replication defective, coronavirus (or more generally nidovirus) particle cell comprises (a) a nidovirus permissive cell; (b) a nidovirus replicon RNA comprising the nidovirus packaging signal and a heterologous RNA sequence, wherein the replicon RNA further lacks a sequence encoding at least one nidovirus structural protein; and (c) at…

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A helper cell for producing an infectious, replication defective, coronavirus (or more generally nidovirus) particle cell comprises (a) a nidovirus permissive cell; (b) a nidovirus replicon RNA comprising the nidovirus packaging signal and a heterologous RNA sequence, wherein the replicon RNA further lacks a sequence encoding at least one nidovirus structural protein; and (c) at least one separate helper RNA encoding the at least one structural protein absent from the replicon RNA, the helper RNA(s) lacking the nidovirus packaging signal. The combined expression of the replicon RNA and the helper RNA in the nidovirus permissive cell produces an assembled nidovirus particle which comprises the heterologous RNA sequence, is able to infect a cell, and is unable to complete viral replication in the absence of the helper RNA due to the absence of the structural protein coding sequence in the packaged replicon. Compositions for use in making such helper cells, along with viral particles produced from such cells, compositions of such viral particles, and methods of making and using such viral particles, are also disclosed.

Patent US7279327B2

From the Reiner/Martin interview:

… in 1999 Anthony Fauci funded research at the University of North Carolina Chapel Hill, specifically to create, and you cannot help but, you know, lament what I’m about to read because this comes directly from a patent application filed on April 19 2002. And you heard the date correctly 2002 where the NIAID built an infectious replication defective Coronavirus that was specifically targeted for human lung epithelium. In other words, we made SARS and we patented it on April 19 2002, before there was ever any alleged outbreak in Asia, which as you know, followed that by several months. That patent issued is US Patent 7279327. That patent clearly lays out in very specific gene sequencing, the fact that we knew that the ACE receptor, the ACE2 binding domain, the s1 spike protein, and other elements of what we have come to know as this scourge pathogen was not only engineered, but could be synthetically modified in the laboratory, using nothing more than gene sequencing technologies, taking computer code and turning it into a pathogen or an intermediate of the pathogen. And that technology was funded exclusively in the early days as a means by which we could actually harness Coronavirus as a vector to distribute HIV vaccine.

Dr. David Martin at 02:53

To see how DNA is generated directly from a computer, see “How We Make DNA” – Cambrian Genomics.

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Ablynx files patent US9193780: Amino acid sequences directed against envelope proteins of a virus and polypeptides comprising the same for the treatment of viral diseases https://pandemictimeline.com/2009/06/ablynx-files-patent-9193780-amino-acid-sequences-directed-against-envelope-proteins-of-a-virus-and-polypeptides-comprising-the-same-for-the-treatment-of-viral-diseases/ Fri, 05 Jun 2009 00:00:35 +0000 https://pandemictimeline.com/?p=1424 The present invention relates in part to amino acid sequences that are directed against and/or that can specifically bind to an envelope protein of a virus, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. — Patent US9193780B2…

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The present invention relates in part to amino acid sequences that are directed against and/or that can specifically bind to an envelope protein of a virus, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.

Patent US9193780B2

From the Reiner/Martin interview:

Dr David Martin  33:24

Oh it does. The 5th of June 2008, which is an important date because it is actually around the time when DARPA the Defence Advanced Research Programme in the United States actively took an interest in Coronavirus as a biological weapon. June 5 2008 Ablynx, which as you know is now part of Sanofi, filed a series of patents that specifically targeted what we’ve been told is the novel feature of the SARS CoV 2 virus. And you heard what I just said, this is the 5th of June 2008.

Reiner Fuellmich  34:09

They found what?

Dr David Martin  34:10

Specifically they targeted what was called the poly basic cleavage site for SARS Cov, the novel spike protein and the ACE2 receptor binding domain which is allegedly novel to SARS CoV 2, and all of that was patented on the 5th of June 2008. And those patents in sequence were issued between November 24th of 2015, which was US Patent 9193780. So that one came out after the gain of function moratorium.

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Cells infected with COVID-19 seen to sprout tentacles. https://pandemictimeline.com/2020/06/cells-infected-with-covid-19-seen-to-sprout-tentacles/ Fri, 26 Jun 2020 00:00:28 +0000 https://pandemictimeline.com/?p=343 Source:

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Salk Institute publishes study showing that spike proteins cause vascular disease. https://pandemictimeline.com/2021/03/salk-institute-publishes-study-showing-that-spike-proteins-cause-vascular-disease/ Wed, 31 Mar 2021 00:00:38 +0000 https://pandemictimeline.com/?p=409 We know now that spike proteins cause blood clots, which in turn damage organs.  Fact checkers are correct in saying that the large visible clots are rare.  But we are now finding out that the spike proteins are causing microscopic clots in the capillaries, which can cause damage to organs where this occurs.  The Canadian…

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We know now that spike proteins cause blood clots, which in turn damage organs.  Fact checkers are correct in saying that the large visible clots are rare.  But we are now finding out that the spike proteins are causing microscopic clots in the capillaries, which can cause damage to organs where this occurs.  The Canadian doctor in a link below explains the mechanism.  This doctor found evidence of capillary level clotting in the majority of his patients.  Note to the US audience:  The Canadian doctor’s pronunciation of the word “capillaries” is so different that it may not be recognizable at first; and yet it is the same word.

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Dr. Judy Mikovits: A potential antidote for the “vaccines” is Suramin https://pandemictimeline.com/2021/04/dr-judy-mikovits-a-potential-antidote-for-the-vaccines-is-suramin/ Tue, 27 Apr 2021 00:00:44 +0000 https://pandemictimeline.com/?p=763 Disclaimer: I am not a medical professional of any kind.   Please consult your medical advisor. What I can tell you, though, is that the COVID-19 “vaccines” are something humanity has not dealt with before. The suggestions below are not guaranteed to work, but they may be your best chance for coping with the ongoing…

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Disclaimer: I am not a medical professional of any kind.   Please consult your medical advisor. What I can tell you, though, is that the COVID-19 “vaccines” are something humanity has not dealt with before. The suggestions below are not guaranteed to work, but they may be your best chance for coping with the ongoing health issues that may result from taking “vaccines” designed to create spike proteins.  No one yet really knows for sure what will help, though some treatments are showing promise.

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“Vaccine-Induced Covid-19 Mimicry” Syndrome https://pandemictimeline.com/2021/05/vaccine-induced-covid-19-mimicry-syndrome/ Wed, 26 May 2021 00:00:28 +0000 https://pandemictimeline.com/?p=596 As of April 2021, four adenovirus vector vaccines for COVID-19 have been authorized in at least one country: The Oxford–AstraZeneca vaccine uses the modified chimpanzee adenovirus ChAdOx1 Sputnik V uses human adenovirus serotype 26 for the first shot and serotype 5 for the second. The Johnson & Johnson vaccine uses serotype 26. Convidecia uses serotype 5. Research article excerpt: During the last months many countries have…

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As of April 2021, four adenovirus vector vaccines for COVID-19 have been authorized in at least one country:

Research article excerpt:

During the last months many countries have started the immunization of millions of people by using vector-based vaccines. Unfortunately, severe side effects became overt during these vaccination campaigns: cerebral venous sinus thromboses (CVST), absolutely rare under normal life conditions, were found as a severe side effect that occured 4-14 days after first vaccinations.

The research is saying that these vaccines can cause blood clots 4 to 14 days after vaccination.

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Japan shares biodistribution study of Pfizer COVID-19 vaccine https://pandemictimeline.com/2021/05/japan-shares-biodistribution-study-of-pfizer-covid-19-vaccine/ Thu, 27 May 2021 00:00:26 +0000 https://pandemictimeline.com/?p=995 The designers of the COVID-19 vaccines expected the contents of a jab to remain in the muscular tissue where they were injected, usually an arm.  This assumption was wrong.  A study document obtained from the Japanese regulatory agency shows that the vaccine contents enter the bloodstream and travel to the various organs.  Lab animals injected with…

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The designers of the COVID-19 vaccines expected the contents of a jab to remain in the muscular tissue where they were injected, usually an arm.  This assumption was wrong.  A study document obtained from the Japanese regulatory agency shows that the vaccine contents enter the bloodstream and travel to the various organs.  Lab animals injected with purified spike protein into their bloodstream developed cardiovascular problems, and the spike protein was also demonstrated to cross the blood brain barrier and cause damage to the brain.

It is important to pay attention to what is going on here.  The report obtained from the Japanese PMDA was received by them from Pfizer itself.  And yet Dr. Byram Bridle and Dr. Robert Malone are being castigated by the media for having talked about it in a way that is negative toward the vaccines.  Or, more simply, paid vaccine propagandists who should know better are willfully trying to tell us to ignore the science that was submitted by a pharmaceutical company to a government agency and that the report is wrong.  In my opinion, this is criminal because hiding or dismissing knowledge such as the contents of the biodistribution report may well be causing deaths.  Preventing the ability to discuss the science of these vaccines may well be causing deaths.  Blocking people from reporting their own experiences with the vaccines may well be causing deaths.  Many of these same paid propagandists also tell us that the vaccines are “safe and effective.”  This actually is a crime.  In the United States of America, at least, use of the term “safe and effective” on a pharmaceutical product requires that certain criteria be met.  Those criteria have not been met for any of the COVID-19 vaccines.  All of the COVID-19 vaccines are still undergoing testing.  Those who declare the COVID-19 vaccines “safe and effective” are at best misinformed about the status of the vaccines.  At worst, they are outright lying to us.

As of August 23, 2021, the Pfizer-BioNTech inoculation is now approved under the brand name Comirnaty. The Comirnaty/Pfizer-BioNTech Fact Sheet for Healthcare Providers Administering Vaccine clearly states that pre-authorization Pfizer-BioNTech vaccine and the Comirnaty vaccine are equivalent. Any objections based on the experimental status of this vaccine are now moot. The argument now becomes whether that approval was legal. Dr. Jane Ruby and Karen Kingston both have concerns about the legality of the approval. See the post about the approval for details.

  • Food & Drug Administration
    October 20, 2021. “Fact Sheet for Healthcare Providers Administering Vaccine [Pfizer-BioNTech].” US Food & Drug Administration. https://www.fda.gov/media/144413/download.
    Food & Drug Administration.
    This document has instructions for healthcare providers who are administering the vaccines.

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  • Research Journal Pfizer PDF
    SARS-CoV-2 MRNA Vaccine (BNT162, PF-0 7302048)2.6.4 薬物動態試験の概要文.” Pfizer-BioNTech, reported to Japan’s Pharmaceuticals and Medical Devices Agency (PMDA).
    Local copy.
    Research Journal, Pfizer, PDF.
    This is the original report in Japanese.  This is also known as the Biodistribution Report. Dr. Byram Bridle together with other international scientists obtained this report by information request from Japan’s Pharmaceuticals and Medical Devices Agency (PMDA). This report was produced by Pfizer-BioNTech and submitted to Japan’s PMDA, In other words, this is the report submitted by the manufacturer to Japan’s government regulatory agency. If the provenance is correct, “fact checkers” cannot debunk this report. Assuming that the provenance is correct, this report is the fact by which “fact checkers” should be checking other statements. Where “fact checkers” have tried to challenge this report, it shows the desperation of some parties to make this report go away, and this exposes them. If you see a “fact checker” trying to debunk this report without proof of bad provenance, you now know that you can no longer trust that “fact checker,” and that probably should extend to the company he works for as well.
  • Research Journal Pfizer PDF
    SARS-CoV-2 MRNA Vaccine (BNT162, PF-07302048) 2.6.4 Summary of Pharmacokinetic Study.
    Local copy.
    Research Journal, Pfizer, PDF.
    This is the same report translated into English, likely by running it through Google Translate without fixing the in-paragraph forced line breaks.  This is likely why the language in the report is a bit rough.  To get a better translation, copy the paragraphs into an editor and change the forced line breaks into spaces.  Then run that text through Google Translate.  If the line breaks are not fixed, Google Translate will consider the line breaks to be the ends of the sentences when the sentences actually cross into the next line.  The line breaks create some strange context for the automatic translator that can seriously impact the results.  Perhaps at some point, I’ll prepare a new translation that way.  That will take some time to do.  But for now, this one at least provides an idea of what was said in the original report.
  • Research Journal PDF
    2021. Alana F. Ogata, Chi-An Cheng, Michaël Desjardins, Yasmeen Senussi, Amy C. Sherman, Megan Powell, Lewis Novack, Salena Von, , Xiaofang Li, Lindsey R. Baden, and David R. Walt. “Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of MRNA-1273 Vaccine Recipients.
    https://uncoverdc.com/wp-content/uploads/2021/05/Bridle.pdf.pagespeed.ce.aKOeaMY9Wh.pdf.
    Research Journal, PDF.
  • Audio
    May 27, 2021. Alex Pierson. “New Peer Reviewed Study on COVID-19 Vaccines Suggests Why Heart Inflammation, Blood Clots and Other Dangerous Side Effects Occur.” ON Point with Alex Pierson – Omny.Fm. Runtime of embedded audio: 9:11.
    https://omny.fm/shows/on-point-with-alex-pierson/new-peer-reviewed-study-on-covid-19-vaccines-sugge.
    Audio.
  • News
    May 31, 2021. “Vaccine Researcher Admits ‘Big Mistake,’ Says Spike Protein Is Dangerous ‘Toxin.’Life Site News.
    https://www.lifesitenews.com/news/vaccine-researcher-admits-big-mistake-says-spike-protein-is-dangerous-toxin/.
    News.
  • News
    May 28, 2021. “Did Pfizer Fail to Perform Industry Standard Animal Testing Prior to Initiation of MRNA Clinical Trials?” TrialSiteNews.
    https://trialsitenews.com/did-pfizer-fail-to-perform-industry-standard-animal-testing-prior-to-initiation-of-mrna-clinical-trials/.
    News.
  • Video Expert
    June 13, 2021. [DarkHorse Podcast Clips]. “Spike Protein Is Very Dangerous, It’s Cytotoxic (Robert Malone, Steve Kirsch, Bret Weinstein).” Runtime: 15:29.
    https://www.youtube.com/watch?v=Du2wm5nhTXY.
    Video, Expert.

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Dr. Richard Fleming explains the COVID-19 situation https://pandemictimeline.com/2021/06/dr-richard-fleming-explains-the-covid-19-situation/ Sat, 05 Jun 2021 00:00:49 +0000 https://pandemictimeline.com/?p=1640 Dr. Richard Fleming presents ‘Event 2021’, a science-based presentation on the COVID-19 pandemic, from the virus, to vaccines, treatments, and the Public Health response.  Virtually everything in this presentation is backed by documentation. If you have time for it, this is probably the best information out there on COVID-19.  Perhaps you can view it in…

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Dr. Richard Fleming presents ‘Event 2021’, a science-based presentation on the COVID-19 pandemic, from the virus, to vaccines, treatments, and the Public Health response.  Virtually everything in this presentation is backed by documentation.

If you have time for it, this is probably the best information out there on COVID-19.  Perhaps you can view it in multiple sessions if time is tight.

Dr. Fleming explains how the virus came to be.  Yes, it was lab-created.  Dr. Fleming shows imaging of the virus.  Scientists know that there is a virus because they can see it with their instruments.  They have sequenced the DNA of the virus and can identify it.  The information shared by Dr. Fleming differs somewhat from that shared by Dr. David Martin.  The main actors in the story are the same, though.

Dr. Fleming explains some early work on finding cures.  It is important to know that generally doctors were told that there were no treatment.  And if doctors tried to use methods of treatment that were not on some official list, they could lose their licenses.  In other words, doctors were prevented under threat from trying methods and drugs that they thought might work.  It is quite possible that many of the people who died could have been saved had doctors been allowed their usual discretion to choose medicines for their patients as they saw fit.

Dr. Fleming talks about choosing medications not for the diseases for which they were approved, but rather for the mechanisms by which they work.  He showed a chart he had made of mechanisms of COVID-19 with a list of drugs and the viral mechanisms they could inhibit.  He and his colleagues had conducted a test of various medications including HCQ.  He explains the protocols of the test.

The presentation includes a video appearance by Dr. Li-Meng Yan, a scientist from Hong Kong who explains what she found when she searched for the origins of SARS-COV-2 and how it appears to be a bioweapon.

Dr. Fleming presents ways we can help with the legal efforts to prevent abuse from the government.

Dr. Fleming presents treatment plans for COVID-19 and spike proteins resulting from jabs.  These are downloadable.

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Related:

  • Research Journal
    September 14, 2020. Li-Meng Yan, Shu Kang, Jie Guan, and Shanchang Hu. “Unusual Features of the SARS-CoV-2 Genome Suggesting Sophisticated Laboratory Modification Rather Than Natural Evolution and Delineation of Its Probable Synthetic Route,
    https://doi.org/10.5281/zenodo.4028830.
    Research Journal.
    Full report.
    The publication note from 17 July 2021 shown with the abstract is interesting to say the least.
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The Science Suggests a Wuhan Lab Leak https://pandemictimeline.com/2021/06/the-science-suggests-a-wuhan-lab-leak/ Sun, 06 Jun 2021 00:00:11 +0000 https://pandemictimeline.com/?p=591 Source:

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Illustration for the Wall Street Journal Opinion piece by Quay and Muller

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